The role of myo-inositol in multiple sclerosis.

AUTOR(ES)

Young, G B

RESUMO

Myo-inositol was given orally to nine multiple sclerosis patients and nine healthy control subjects. Pattern reversal evoked potential testing was used to assess its effect. The principal positive wave increased in amplitude, duration and area in a dose-dependent manner in the multiple sclerosis group compared with controls. Cerebrospinal fluid concentrations of myo-inositol in multiple sclerosis and controls were similar. The significance of these observations is discussed in relation to recent discoveries in inositol phospholipid function.

Documentos Relacionados

• Myo-inositol transport in Saccharomyces cerevisiae.
• Myo-inositol transport system in Pseudomonas putida.
• Regulation of myo-Inositol Catabolism in Aerobacter aerogenes
• Metabolism of myo-inositol during sporulation of myo-inositol-requiring Saccharomyces cerevisiae.
• Turtles All the Way: Reflections on myo-Inositol