The role of bisphosphonates in breast cancer: The present and future role of bisphosphonates in the management of patients with breast cancer
AUTOR(ES)
Brown, Janet E
FONTE
BioMed Central
RESUMO
At least 25% of patients with breast cancer develop skeletal metastases, with bone the site of disease producing the greatest morbidity. It is apparent that the bisphosphonates present an important component of the treatment strategy. They are now the treatment of choice in tumour-induced hypercalcaemia, and they can reduce bone pain and skeletal complications such as pathological fractures. In addition, bisphosphonates are being increasingly evaluated in the prevention of bone metastases and to prevent and treat cancer therapy-induced osteoporosis. Ongoing research is aimed at trying to define the optimum route, dose, schedule and type of bisphosphonate.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=138712Documentos Relacionados
- The role of bisphosphonates in breast cancer: Development of bisphosphonates
- The role of bisphosphonates in breast cancer: Direct effects of bisphosphonates on breast cancer cells
- The role of bisphosphonates in breast cancer: Actions of bisphosphonates in animal models of breast cancer
- Future possibilities in the prevention of breast cancer: Role of genetic variation in breast cancer prevention
- Future possibilities in the prevention of breast cancer: Breast cancer prevention trials
