The effect of therapies on the quality of life of patients with systemic lupus erythematosus: a meta-analysis of randomized trials
AUTOR(ES)
Hora, Tassia Catiuscia da
FONTE
Adv. rheumatol.
DATA DE PUBLICAÇÃO
08/08/2019
RESUMO
Abstract Introduction Systemic lupus erythematosus (SLE) is a multi-systemic, chronic inflammatory disease of autoimmune nature, which can impair performance in daily life activities, causing to a compromised quality of life. Thus, the aim of this study was to evaluate the effect of therapies, such as physical activity, cognitive behavioral therapy, pharmacological treatment and phytotherapy in the quality of life of patients with systemic lupus erythematosus. Materials and methods A systematic review with a meta-analysis of randomized clinical trials was conducted by searching the PubMed database, including studies comparing patients who participated in cognitive therapy, physical activity, pharmacological treatment or phytotherapeutic treatment. Results Of the seven studies included in this meta-analysis, a significant difference was observed in the quality of life of patients with lupus who participated in the intervention groups compared to the control groups (− 10.27 95% CI: − 15, 77 at − 4.77, p = 0.0003, I2 = 0%). Conclusion Interventions improve the Quality of life of patients with SLE. However, the methodological quality of the included articles and the sizes of the samples for being small propose that new randomized clinical trials be performed.
Documentos Relacionados
- Association between tumor necrosis factor polymorphisms and rheumatoid arthritis as well as systemic lupus erythematosus: a meta-analysis
- Association between pemphigus and systemic lupus erythematosus: a systematic review and meta-analysis,
- Clinical effect of different dialyzers used in patients with kidney disease: a meta-analysis of randomized clinical trials
- Psychoanalytic psychotherapy improves quality of life, depression, anxiety and coping in patients with systemic lupus erythematosus: a controlled randomized clinical trial
- The effect of school-based physical activity interventions on body mass index: a meta-analysis of randomized trials