The Effect of Genetic Linkage on the Mean Fitness of a Population

AUTOR(ES)

Lewontin, R. C.

RESUMO

If many gene loci are kept in a segregating state by natural selection, the equilibrium frequencies of the genotypes in the population may be a function of the amount of recombination among the genes. It is shown that if the equilibrium vector of gametic frequencies is a continuous function of the set of recombination frequencies among genes, then the mean fitness of the population at equilibrium is a maximum in the absence of recombination. Thus, in general, restriction of recombination increases fitness.

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