The effect of diphenylhydantoin on metabolic and growth hormone changes during and after exercise.
AUTOR(ES)
Chalmers, R J
RESUMO
Metabolic and human growth hormone responses to exercise were investigated in six normal healthy subjects on two occasions with and without an oral dose of diphenylhydantoin (500 mg). Serum diphenylhydantoin concentrations were similar in all subjects and were just below the accepted therapeutic range for epileptic patients. There was no significant difference in blood lactate, pyruvate or glucose concentrations with diphenylhydantoin. Plasma free fatty acids, and blood glycerol and total ketone concentrations were greater after exercise following diphenylhydantoin. Significantly greater concentrations of human growth hormone occurred during exercise with diphenylhydantoin. Further investigation of the mechanisms by which diphenylhydantoin alters lipolysis and human growth hormone release would be of value as these metabolic and hormonal effects could influence exercise tolerance in athletics and other pursuits.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1027488Documentos Relacionados
- Haemodynamic changes during continuous exercise.
- Metabolic and ventilatory changes in asthmatic patients during and after exercise
- Metabolic heterogeneity in human calf muscle during maximal exercise.
- Circulatory changes in acute glomerulonephritis at rest and during exercise.
- Changes in the inotropic state of the left ventricle during isometric exercise.
