The 5′ Untranslated Region of Alfalfa Mosaic Virus RNA 1 Is Involved in Negative-Strand RNA Synthesis
AUTOR(ES)
Vlot, A. Corina
FONTE
American Society for Microbiology
RESUMO
The three genomic RNAs of alfalfa mosaic virus each contain a unique 5′ untranslated region (5′ UTR). Replacement of the 5′ UTR of RNA 1 by that of RNA 2 or 3 yielded infectious replicons. The sequence of a putative 5′ stem-loop structure in RNA 1 was found to be required for negative-strand RNA synthesis. A similar putative 5′ stem-loop structure is present in RNA 2 but not in RNA 3.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=224982Documentos Relacionados
- Role of the Alfalfa Mosaic Virus Methyltransferase-Like Domain in Negative-Strand RNA Synthesis
- Sindbis virus nsP1 functions in negative-strand RNA synthesis.
- Mutation of Host dnaJ Homolog Inhibits Brome Mosaic Virus Negative-Strand RNA Synthesis
- Nonhomologous RNA recombination during negative-strand synthesis of flock house virus RNA.
- Translating Ribosomes Inhibit Poliovirus Negative-Strand RNA Synthesis
