Synthesis of vitellogenin in cultures of male and female frog liver regulated by estradiol treatment in vitro.

AUTOR(ES)

Wangh, L J

RESUMO

Using the frog Xenopus laevis, we show that the addition of physiological concentrations of estradiol to cultures of liver from untreated males rapidly induces the synthesis of large amounts of vitellogenin. Sustained synthesis of vitellogenin requires continuous exposure to estradiol. A nonestrogenic steroid, dexamethasone, does not induce vitellogenin synthesis but does induce increased synthesis of a different protein in liver cultures.

Documentos Relacionados

• Specific modulation of the transcription of cloned avian vitellogenin II gene by estradiol-receptor complex in vitro.
• Induction of vitellogenin synthesis by estrogen in avian liver: relationship between level of vitellogenin mRNA and vitellogenin synthesis.
• Apolipoprotein B synthesis by human liver and intestine in vitro.
• Coordination of ribosome content and polysome formation during estradiol stimulation of vitellogenin synthesis in immature male chick livers.
• Expression of the vitellogenin gene in female and male sea urchin.