SYNTHESIS OF SERINE BY COXIELLA BURNETII

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Myers, W. F. (University of Kansas, Lawrence) and D. Paretsky. Synthesis of serine by Coxiella burnetii. J. Bacteriol. 82:761–763. 1961.—Enzyme preparations from suspensions of purified Coxiella burnetii are capable of synthesizing serine from formaldehyde and glycine-2-C14 in the presence of tetrahydrofolic acid. Evidence for the reaction is obtained by isolating and identifying radioactive serine and serine derivatives. The data suggest a role for folic acid in these rickettsiae, and extend the knowledge of host-independent biosynthetic competencies of these highly parasitic microorganisms.

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