Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues

AUTOR(ES)

Rodríguez, Caridad R., Villalobos, Yohan I., Becerra, Esther A., Manchado, Francisco C., Herrera, Deysma C., Zullo, Marco A. T.

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2003-05

RESUMO

Três novos análogos espirostânicos de brassinosteróides foram sintetizados pela primeira vez a partir de diosgenina: (25R)-2alfa,3alfa-epoxi-5alfa-hidroxiespirostan-6-ona (3), (25R)-2beta,3alfa,5alfa-triidroxiespirostan-6-ona (5) e (25R)-2beta-metoxi-3alfa,5alfa-diidroxiespirostan-6-ona (6). A substância 3 mostrou acentuada atividade promotora de crescimento vegetal no bioensaio de elongação do hipocótilo e expansão do cotilédone de rabanete, enquanto a substância 6 mostrou-se fitotóxica.

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