Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA

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BioMed Central

RESUMO

Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation.

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