Synchronization between prefrontal and posterior association cortex during human working memory

AUTOR(ES)

Sarnthein, J.

FONTE

The National Academy of Sciences

RESUMO

We measured coherence between the electroencephalogram at different scalp sites while human subjects performed delayed response tasks. The tasks required the retention of either verbalizable strings of characters or abstract line drawings. In both types of tasks, a significant enhancement in coherence in the θ range (4–7 Hz) was found between prefrontal and posterior electrodes during 4-s retention intervals. During 6-s perception intervals, far fewer increases in θ coherence were found. Also in other frequency bands, coherence increased; however, the patterns of enhancement made a relevance for working memory processes seem unlikely. Our results suggest that working memory involves synchronization between prefrontal and posterior association cortex by phase-locked, low frequency (4–7 Hz) brain activity.

Documentos Relacionados

• Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task.
• Competition and representation during memory retrieval: Roles of the prefrontal cortex and the posterior parietal cortex
• Dissociation in human prefrontal cortex of affective influences on working memory-related activity
• Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.
• Prefrontal cortex and episodic memory retrieval mode