Sweet syndrome associated with secondary nodular syphilis in an immunocompetent patient

AUTOR(ES)

Escanilla, Claudio; Goldman, Yerco; Bobadilla, Francisco; Segovia, Laura

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

2021-06

RESUMO

Abstract Sweet syndrome is an inflammatory disease characterized by fever, neutrophilia, papules and erythematous plaques, and a skin neutrophilic infiltrate. Syphilis has been reported among the infectious causes of Sweet syndrome. Syphilis can present atypical manifestations; a rare presentation is nodular syphilis, characterized by nodules with granulomas and plasma cells at histopathology. This case report presents a 20-year-old woman patient, with plaques and nodules, and systemic symptoms. The histopathological exam revealed both non-tuberculoid granulomas and a dense infiltration of polymorphonuclear neutrophils in the dermis. These findings, plus laboratory abnormalities, characteristic of both conditions, were conclusive for Sweet syndrome and nodular syphilis association.

Documentos Relacionados

• Nodular tertiary syphilis in an immunocompetent patient
• Malignant syphilis in an immunocompetent female patient
• Toxoplasma gondii-Associated Guillain-Barré Syndrome in an Immunocompetent Patient
• Disseminated cutaneous sporotrichosis associated with ocular lesion in an immunocompetent patient
• Staphylococcal scalded skin syndrome in an adult, immunocompetent patient