Sugar-mediated induction of Agrobacterium tumefaciens virulence genes: structural specificity and activities of monosaccharides.
AUTOR(ES)
Ankenbauer, R G
RESUMO
The virulence genes of Agrobacterium tumefaciens are induced by specific plant phenolic metabolites and sugars (G. A. Cangelosi, R. G. Ankenbauer, and E. W. Nester, Proc. Natl. Acad. Sci. USA, in press). In this report, monosaccharides, derivatives, and analogs which induce the vir regulon have been identified and the structural requirements for monosaccharide-mediated induction have been determined. Pyranose sugars with equatorial hydroxyls at C-1, C-2, and C-3 displayed strong vir gene-inducing activity; the C-4 hydroxyl could be epimeric and a wide variety of substitutions at C-5 were permissible. The acidic monosaccharide derivatives D-galacturonic acid and D-glucuronic acid were the strongest inducers among the monosaccharides tested. Eight of the 11 inducing compounds are known plant metabolites, and 7 are monomers of major plant cell wall polysaccharides. A role for monosaccharides and plant phenolic compounds as wound-specific plant metabolites which signal the ChvE/VirA/VirG regulatory system is proposed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=526831Documentos Relacionados
- Sugar Sensing and Sugar-Mediated Signal Transduction in Plants.
- Sugar-mediated acclimation: the importance of sucrose metabolism in meristems.
- Control of expression of Agrobacterium vir genes by synergistic actions of phenolic signal molecules and monosaccharides.
- Promoters of Agrobacterium tumefaciens Ti-plasmid virulence genes.
- Dual control of Agrobacterium tumefaciens Ti plasmid virulence genes.
