Subinhibitory concentrations of antibiotics alter fibronectin binding to Staphylococcus aureus.
AUTOR(ES)
Proctor, R A
RESUMO
Fibronectin, a high-molecular-weight glycoprotein, is found in plasma and on mammalian cell surfaces. Recent reports have suggested that bacterial-fibronectin interactions play a role in bacterial attachment to host cells. Subinhibitory concentrations of lincosamines, erythromycin, and chloramphenicol decreased fibronectin binding to Staphylococcus aureus, whereas beta-lactam antibiotics enhanced this interaction.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=185954Documentos Relacionados
- Isolation of a fibronectin-binding protein from Staphylococcus aureus.
- Subinhibitory concentrations of imipenem induce increased resistance to methicillin and imipenem in vitro in methicillin-resistant Staphylococcus aureus.
- Fibronectin enhances transfection of Staphylococcus aureus.
- Increased expression of fibronectin-binding proteins by fluoroquinolone-resistant Staphylococcus aureus exposed to subinhibitory levels of ciprofloxacin.
- Collagen binding to Staphylococcus aureus.
