Studies on trigonelline from Moringa oleifera and its in vitro regulation by feeding precursor in cell cultures

AUTOR(ES)

Mathur, Manas, Kamal, Raka

FONTE

Rev. bras. farmacogn.

DATA DE PUBLICAÇÃO

03/04/2012

RESUMO

Trigonelline (N-methylnicotinate) biosynthesized from nicotinate is one of the metabolically active pyridine alkaloid, widely distributed in plant kingdom. In the present study trigonelline has been isolated from various plant parts and callus cultures of Moringa oleifera Lam., Moringaceae, and was identified using TLC, GLC, GC-MS, which was comparable to that of the standard trigonelline. The trigonelline recovery was found to be maximum in the pods and minimum in flowers. In order to enhance the production of trigonelline in vitro grown cultures, different treatment doses of nicotinic acid (250, 500 and 750 mg L-1) were supplemented in the medium as precursor. Maximum increase (up to 1.10 fold) was observed in the treatment dose of 500 mg L-1 of nicotinic acid.

Documentos Relacionados

• PropagaÃÃo in vitro de Moringa oleifera L.
• Inclusion of Moringa Leaf Powder (Moringa oleifera) in Fodder for Feeding Japanese Quail (Coturnix coturnix japonica)
• Biosorption and removal of chromium from water by using moringa seed cake (Moringa oleifera Lam.)
• Biological evaluation of crude and degummed oil from Moringa oleifera seeds
• Efeito antibacteriano (in vitro) de Moringa oleifera (moringa) e Annona muricata (graviola) frente a bactérias Gram-negativas e Gram-positiva