Studies on the Action of Nalidixic Acid in the Yeast Saccharomyces cerevisiae
AUTOR(ES)
Michels, C. A.
RESUMO
The effect of the antibiotic nalidixic acid on macromolecular metabolism in the yeast Saccharomyces cerevisiae has been studied. It was found that, upon the addition of nalidixic acid to a logarithmically growing culture, there is a transient inhibition of total cell ribonucleic acid, deoxyribonucleic acid, and protein synthesis, after which the cells show an almost complete recovery. In addition, there is no preferential inhibition of yeast mitochondrial deoxyribonucleic acid synthesis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=444458Documentos Relacionados
- Studies on the Mechanism of Action of Nalidixic Acid
- Toxicity of Nalidixic Acid on Candida albicans, Saccharomyces cerevisiae, and Kluyveromyces lactis
- Mechanism of Action of Nalidixic Acid on Escherichia coli VI. Cell-free Studies
- Action of Deflocculating Agents on Saccharomyces cerevisiae Class III Brewer's Yeast
- STUDIES ON THE SYNTHESIS OF RIBOFLAVIN BY A MUTANT YEAST, SACCHAROMYCES CEREVISIAE