Statistical analysis of mammalian pre-mRNA splicing sites.

AUTOR(ES)

Gelfand, M S

RESUMO

222 donor and 222 acceptor (including 206 pairs) non-homologous splicing sites were studied. Well known features of these were confirmed and some novel observations were made. It is (1) cCAGGGag signal in (-60)-(-58) region of acceptor sites; (2) strong complementarity between regions (-69)-(-55) and (-36)-(-22) of some of the acceptor sites, and (3) small but statistically significant correlation between discrimination energies of corresponding donor and acceptor sites.

Documentos Relacionados

• The human splicing factor ASF/SF2 can specifically recognize pre-mRNA 5' splice sites.
• Polyoma virus small tumor antigen pre-mRNA splicing requires cooperation between two 3' splice sites.
• A coactivator of pre-mRNA splicing
• Functional analysis of the polypyrimidine tract in pre-mRNA splicing.
• RNA helicase dynamics in pre-mRNA splicing