Static and dynamic lung volumes and ventilation-perfusion abnormality in adult asthma

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RESUMO

Dynamic lung volumes (forced vital capacity, forced expiratory volume in 0·5 second and in 1·0 second), static lung volumes (total lung capacity, functional residual capacity, residual volume), and ventilation-perfusion relationships (alveolar-arterial oxygen tension difference, alveolar dead space ventilation to tidal volume ratio, arterial oxygen and carbon dioxide tension, and the fractional ventilation and perfusion relationship by the three-compartment lung model) were measured in adult asthmatics during the acute, recovery, and stable or asymptomatic phases of an asthmatic attack. Eighteen patients were studied during 20 separate asthmatic attacks.

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