Stability of DNA fingerprint pattern produced with IS6110 in strains of Mycobacterium tuberculosis.
AUTOR(ES)
Cave, M D
RESUMO
To assess the stability of IS6110 restriction fragment length polymorphism patterns, DNA fingerprints of 6 Mycobacterium bovis isolates from 1 patient and of 41 Mycobacterium tuberculosis isolates from 18 patients were compared. The fingerprint pattern for a given patient remained identical or nearly identical despite recovery of the isolates during intervals which ranged from 8 months to 4.5 years. Changes in drug resistance profile did not alter a strain's fingerprint pattern.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=263014Documentos Relacionados
- Chromosomal DNA fingerprint patterns produced with IS6110 as strain-specific markers for epidemiologic study of tuberculosis.
- Calculation of the Stability of the IS6110 Banding Pattern in Patients with Persistent Mycobacterium tuberculosis Disease
- Stability of IS6110 Restriction Fragment Length Polymorphism Patterns of Multidrug-Resistant Mycobacterium tuberculosis Strains
- Evolutionary Relationships among Strains of Mycobacterium tuberculosis with Few Copies of IS6110
- Heminested inverse PCR for IS6110 fingerprinting of Mycobacterium tuberculosis strains.