Specificity of Human Antibodies Reactive with Pneumococcal C Polysaccharide

AUTOR(ES)

Frasch, Carl E.

FONTE

American Society for Microbiology

RESUMO

Antibodies reactive with C polysaccharide (PS) were found in healthy adults, pneumococcal patients, and vaccinees. These antibodies were not directed to the phosphocholine determinant of the C PS, as they appear to be in mice, since the human antibodies were inhibitable only with C PS. We found another population of phosphocholine-specific antibodies inhibitable only by phosphocholine and related compounds.

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