Specific Interaction of Feline Immunodeficiency Virus Surface Glycoprotein with Human DC-SIGN
AUTOR(ES)
de Parseval, Aymeric
FONTE
American Society for Microbiology
RESUMO
DC-SIGN, a specific C-type lectin expressed on dendritic cells, binds and transmits multiple strains of primate immunodeficiency viruses to susceptible cells. Here, we report that human DC-SIGN also captures feline immunodeficiency virus via high-affinity (1 nM), Ca2+-dependent, d-mannose-inhibited binding to the major envelope glycoprotein, gp95.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=369267Documentos Relacionados
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