Some rat sensory neurons in culture express characteristics of differentiated pain sensory cells.
AUTOR(ES)
Baccaglini, P I
RESUMO
Sensory neurons were dissociated from trigeminal ganglia or from dorsal root ganglia of rats, grown in culture, and examined for expression of properties of pain sensory cells. Many sensory neurons in culture are excited by low concentrations of capsaicin, reportedly a selective stimulus for pain sensory neurons. Many are excited by bradykinin, sensitized by prostaglandin E2, or specifically stained by an antiserum against substance P. These experiments provide a basis for the study of pain mechanisms in cell culture.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=393426Documentos Relacionados
- Peripheral infection in culture of rat sensory neurons by herpes simplex virus.
- Expression of catecholaminergic characteristics by primary sensory neurons in the normal adult rat in vivo.
- Postmortem survival characteristics of rat glial cells in culture.
- Effects of lectins on peripheral infections by herpes simplex virus of rat sensory neurons in culture.
- Functional characteristics of dispersed rat submandibular cells.