Some effects of ultrasound on guinea-pig ear skin

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Carney, S. A., Lawrence, J. C., and Ricketts, C. R. (1972).Brit. J. industr. Med.,29, 214-220. Some effects of ultrasound on guinea-pig ear skin. Slices of guinea-pig ear skin were irradiated with ultrasound of frequency 3 MHz for 30 seconds at various power densities. After irradiation the specimens were incubated on a nutrient medium for 24 hours. Measurements of the uptake of 32PO43- and 35SO42-, skin cell respiration, and dehydrogenase activity were then made. In each case a graded inhibition with increasing power density was observed. These inhibitions were attributed to thermal damage of the skin cells, a view consistent with the histological appearance of the specimens.

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