SKN7 of Candida albicans: Mutant Construction and Phenotype Analysis
AUTOR(ES)
Singh, Praveen
FONTE
American Society for Microbiology
RESUMO
The SKN7 two-component response regulator gene of Candida albicans was deleted, and the phenotype of the mutant was established. This mutant exhibited impaired growth on Spider agar and 10% serum agar compared to wild-type and gene-reconstituted strains. The skn7 mutant was sensitive to H2O2 in vitro, but its virulence was only mildly attenuated. A comparison of the Skn7p and Ssk1p response regulators of C. albicans is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=375215Documentos Relacionados
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