Sex-specific cognitive abnormalities in early-onset psychosis

AUTOR(ES)

Ruiz-Veguilla, Miguel, Moreno-Granados, Josefa, Salcedo-Marin, Maria D., Barrigon, Maria L., Blanco-Morales, Maria J., Igunza, Evelio, Cañabate, Anselmo, Garcia, Maria D., Guijarro, Teresa, Diaz-Atienza, Francisco, Ferrin, Maite

FONTE

Rev. Bras. Psiquiatr.

DATA DE PUBLICAÇÃO

09/01/2017

RESUMO

Objectives: Brain maturation differs depending on the area of the brain and sex. Girls show an earlier peak in maturation of the prefrontal cortex. Although differences between adult females and males with schizophrenia have been widely studied, there has been less research in girls and boys with psychosis. The purpose of this study was to examine differences in verbal and visual memory, verbal working memory, auditory attention, processing speed, and cognitive flexibility between boys and girls. Methods: We compared a group of 80 boys and girls with first-episode psychosis to a group of controls. Results: We found interactions between group and sex in verbal working memory (p = 0.04) and auditory attention (p = 0.01). The female controls showed better working memory (p = 0.01) and auditory attention (p = 0.001) than males. However, we did not find any sex differences in working memory (p = 0.91) or auditory attention (p = 0.93) in the psychosis group. Conclusions: These results are consistent with the presence of sex-modulated cognitive profiles at first presentation of early-onset psychosis.

Documentos Relacionados

• Trajectory of brain maturation and sex-specific cognitive abnormalities in early-onset psychosis
• Neuropsychological dysfunction in adults with early-onset obsessive-compulsive disorder: the search for a cognitive endophenotype
• Biometry of the crystalline lens in early-onset diabetes.
• SRY recognizes conserved DNA sites in sex-specific promoters.
• Sex-specific compensatory growth in food-deprived Nile tilapia