Serologic survey of West Nile virus in horses from Central-West, Northeast and Southeast Brazil

AUTOR(ES)

Silva, Jaqueline Raymondi, Medeiros, Larissa Campos de, Reis, Vinícius Pinho dos, Chávez, Juliana Helena, Munhoz, Thiago Demarchi, Borges, Gustavo Puia, Soares, Otavio Augusto Brioschi, Campos, Carlos Henrique Coelho de, Machado, Rosângela Zacarias, Baldani, Cristiane Divan, Silva, Maria Luana Cristiny Rodrigues, Faria, Joice Lara Maia, Silva, Edson Elias da, Figueiredo, Luiz Tadeu Moraes

FONTE

Mem. Inst. Oswaldo Cruz

DATA DE PUBLICAÇÃO

2013-11

RESUMO

Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.

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