Sendai virus infection of mice with protein malnutrition.
AUTOR(ES)
Pena-Cruz, V
RESUMO
Sendai virus pneumonia was produced in BALB/c mice fed protein-deficient diets in an effort to understand the severity of viral pneumonia in infants in developing countries. Animals on the deficient diet became clinically malnourished, and some aspects of cellular immunity were altered. In protein-deprived animals, the 50% lethal dose of intranasally administered Sendai virus was over 1,000-fold lower, pulmonary virus titers were higher, the infection was prolonged, and lung infection was established at a lower inoculum than in normal animals.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=250935Documentos Relacionados
- Xerophthalmia and protein malnutrition.
- Enzyme changes in malnutrition.
- Genetics of natural resistance to Sendai virus infection in mice.
- Mechanisms of depressed delayed-type hypersensitivity in rheumatoid arthritis: the role of protein energy malnutrition.
- Cell-mediated immunity to Sendai virus infection in mice.
