Self-association of Cholesterol in Aqueous Solution

AUTOR(ES)

Haberland, Margaret E.

RESUMO

Cholesterol has a maximum solubility in aqueous solutions of 1.8 μg/ml or 4.7 μM. It undergoes a thermodynamically reversible self-association with a critical micelle concentration of 25 to 40 nM at 25°. The cholesterol micelle is heterogeneous in size, probably rodlike in shape, and stabilized by an unusually high interaction energy between the aggregated monomers.

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