Saturated Fatty Acid Requirer of Neurospora crassa
AUTOR(ES)
Henry, Susan A.
RESUMO
Dietary saturated fatty acids containing 12- to 18-carbon atoms satisfy growth requirements of Neurospora crassa mutant cel (previously named ol; Perkins et al., reference 11); unsaturated fatty acids are synthesized by direct desaturation when an appropriate saturate is available. Odd-chain saturates, 15 carbons and 17 carbons long, satisfy the requirement, and elaidic acid (18:1 Δ9trans) results in slow growth. Oleic acid and other cis-unsaturated fatty acids do not satisfy growth requirements; however, oleic acid plus elaidic acid result in growth at a faster rate than elaidate alone. The use of a spin-label fatty acid reveals that hyphae produced by cel during a slow basal level of growth have lipids that reflect a relatively rigid state of viscosity compared to wild type. cel Supplemented with fatty acids and wild type supplemented in the same way have lipids of the same viscosities as reflected by electron spin resonance.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=248659Documentos Relacionados
- Circadian Rhythms in Neurospora crassa: Effects of Saturated Fatty Acids
- Unsaturated fatty acid mutants of Neurospora crassa.
- Altered Fatty Acid Distribution in Mutants of Neurospora crassa
- Saturated Fatty Acid Mutant of Saccharomyces cerevisiae with an Intact Fatty Acid Synthetase
- Circadian rhythms in Neurospora crassa: effects of unsaturated fatty acids.
