Satisfaction of the uncertainty principle in cancer clinical trials: retrospective cohort analysis

AUTOR(ES)
FONTE

BMJ Publishing Group Ltd.

RESUMO

Objective To assess whether publicly funded adult cancer trials satisfy the uncertainty principle, which states that physicians should enrol a patient in a trial only if they are substantially uncertain which of the treatments in the trial is most appropriate for the patient. This principle is violated if trials systematically favour either the experimental or the standard treatment.

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