Rosai-Dorfman disease with spontaneous resolution: case report of a child
AUTOR(ES)
Lima, Felipe Barbosa, Barcelos, Pedro Samuel de Valões, Constâncio, Ana Paula Nunes, Nogueira, Cleto Dantas, Melo-Filho, Antônio Aldo
FONTE
Revista Brasileira de Hematologia e Hemoterapia
DATA DE PUBLICAÇÃO
2011
RESUMO
Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.
