Role of oxidized low density lipoprotein in atherogenesis.
AUTOR(ES)
Witztum, J L
RESUMO
Evidence to support an important role of oxidative modification in mediating the atherogenicity of LDL continues to grow. New hypotheses suggest mechanisms by which Ox-LDL or products of Ox-LDL can affect many components of the atherogenic process, including vasomotor properties and thrombosis, as well as lesion initiation and progression itself. These ideas suggest new approaches, that in combination with lowering of plasma cholesterol, could lead to the prevention of atherosclerosis and its complications.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=295745Documentos Relacionados
- Oxidised low density lipoproteins and atherogenesis.
- Role of oxidised low density lipoprotein in atherogenesis
- Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.
- Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.
- Role of lysophosphatidylcholine in the inhibition of endothelial cell motility by oxidized low density lipoprotein.