Role of Endogenous Interleukin-12 in Immune Response to Staphylococcal Enterotoxin B in Mice

AUTOR(ES)

Lauw, Fanny N.

FONTE

American Society for Microbiology

RESUMO

In the present study, the roles of interleukin 12 (IL-12) and IL-18 and their possible interaction during superantigen-induced responses were studied by injection of staphylococcal enterotoxin B (SEB) into mice. These data suggest that the role of IL-12 in SEB-induced responses is limited to sustaining gamma interferon release by an IL-18-independent mechanism.

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