Role of Actin Filament Network in Burkholderia multivorans Invasion in Well-Differentiated Human Airway Epithelia

AUTOR(ES)

Schwab, Ute E.

FONTE

American Society for Microbiology

RESUMO

The role of the actin-based cytoskeleton in the internalization process of Burkholderia multivorans by well-differentiated human airway epithelia was investigated by immunohistology and confocal microscopy. Our data suggest that an intact actin cytoskeleton is required for biofilm formation but not single cell entry or paracytosis.

Documentos Relacionados

• Patterns of Epithelial Cell Invasion by Different Species of the Burkholderia cepacia Complex in Well-Differentiated Human Airway Epithelia
• Measles Virus Preferentially Transduces the Basolateral Surface of Well-Differentiated Human Airway Epithelia
• Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia
• Responses of Well-Differentiated Airway Epithelial Cell Cultures from Healthy Donors and Patients with Cystic Fibrosis to Burkholderia cenocepacia Infection
• Limited Entry of Adenovirus Vectors into Well-Differentiated Airway Epithelium Is Responsible for Inefficient Gene Transfer