Risk associated with heparin withdrawal in ischaemic cerebrovascular disease.
AUTOR(ES)
Slivka, A
RESUMO
Intravenous heparin is frequently used to treat thromboembolic disease, but the consequences of stopping heparin have not been studied systematically. To determine whether discontinuing heparin poses a clinical risk, we examined the charts of 378 patients treated with heparin for transient ischaemic attack (TIA), reversible ischaemic neurological deficit, or ischaemic stroke from October 1979 to June 1985. Clinical deterioration, or a new TIA or stroke was more likely (p = 0.01) during the 24 hours after heparin was stopped in patients not already on aspirin or warfarin (10/143, 7%) than in patients receiving aspirin or warfarin before heparin withdrawal (3/215, 1%). Stopping heparin in patients not receiving aspirin or warfarin appears to expose them to an increased risk for TIA, stroke, or clinical deterioration.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1031586Documentos Relacionados
- Echocardiography in ischaemic cerebrovascular disease.
- Sudden versus gradual withdrawal of sotalol in ambulant patients with ischaemic heart disease.
- Ethnic group comparisons of variables associated with ischaemic heart disease.
- Points: Echocardiography in ischaemic cerebrovascular disease
- Angiographic and risk factor characteristics of subjects with early onset ischaemic heart disease.
