Rhinoviruses as critical agents in severe bronchiolitis in infants
AUTOR(ES)
Bastos, Juliana Cristina Santiago; Simas, Paulo Vitor Marques; Caserta, Leonardo Cardia; Bragunde, Alfonso Eduardo Alvarez; Marson, Fernando Augusto de Lima; Martini, Matheus Cavalheiro; Padilla, Marina Aiello; Ribeiro, José Dirceu; Santos, Márcia Mercês Aparecida Bianchi dos; Arns, Clarice Weis
FONTE
Jornal de Pediatria
DATA DE PUBLICAÇÃO
2022
RESUMO
Abstract Objectives: To detect RSV or other thirteen respiratory viruses as possible causer agent of bronchiolitis in infants. Method: This is an epidemiological analytical study, conducted using a nasopharyngeal aspirate of 173 hospitalized children younger than two years old with severe bronchiolitis in three hospitals in the Campinas Metropolitan Region (CMR) during 2013-14. The data was statically evaluated by Pearson’s chi-squared test with statistical significance of 0.05 and 95% confidence level. Results: As expected, the most prevalent viruses detected were RSV A and B in 47% and 16% of the samples, respectively. However, almost a third of severe bronchiolitis cases there were no detection of RSV, and the viruses more commonly detected were rhinoviruses, which were identified in almost a quarter of all positive samples for at least a viral agent. Conclusions: Although nothing could be concluded from the disease severity and clinicalepidemiological data, the present study’s results indicate that severe bronchiolitis is not always related to RSV infections in children younger than two years old, and the rhinoviruses were more prevalent in these cases. These findings reinforce the need to carry out a
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