Requirement of cell nucleus for African swine fever virus replication in Vero cells.
AUTOR(ES)
Ortin, J
RESUMO
The role of the cell nucleus in the development of African swine fever virus in Vero cells has been studied. No viral growth could be detected in enucleated cells under conditions that allow normal development of Sindbis virus. Furthermore, African swine fever virus DNA synthesis was inhibited more than 95% after infection of enucleated Vero cells as compared with normal cells.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=515627Documentos Relacionados
- Requirement of cell nucleus for Sindbis virus replication in cultured Aedes albopictus cells.
- Establishment of a Vero cell line persistently infected with African swine fever virus.
- Inhibition by Rifampin of African Swine Fever Virus Replication in Tissue Culture
- The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine
- African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells.