Repression of the Virulence of Yersinia pestis by an F' Plasmid

AUTOR(ES)
RESUMO

An F-lac plasmid from Escherichia coli was transferred to virulent Yersinia pestis, resulting in the repression of virulence. The Y. pestis F-lac clones retained all of the known virulence traits but were avirulent and calcium independent. Every lac segregant derived from the F-lac clones was fully virulent and calcium dependent.

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