Repair of Radiation-Induced Damage to the Cell Division Mechanism of Escherichia coli1
AUTOR(ES)
Adler, Howard I.
RESUMO
Adler, Howard I. (Oak Ridge National Laboratory, Oak Ridge, Tenn.), William D. Fisher, Alice A. Hardigree, and George E. Stapleton. Repair of radiation-induced damage to the cell division mechanism of Escherichia coli. J. Bacteriol. 91:737–742. 1966.—Microscopic observations of irradiated populations of filamentous Escherichia coli cells indicated that filaments can be induced to divide by a substance donated by neighboring cells. We have made this observation the basis for a quantitative technique in which filaments are incubated in the presence of nongrowing donor cells. The presence of “donor” organisms promotes division and subsequent colony formation in filaments. “Donor” bacteria do not affect nonfilamentous cells. An extract of “donor” cells retains the division-promoting activity. The extract has been partially fractionated, and consists of a heat-stable and a heat-labile component. The heat-stable component is inactive in promoting cell division, but enhances the activity of the heat-labile component. The division-promoting system is discussed as a radiation repair mechanism and as a normal component of the cell division system in E. coli.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=314922Documentos Relacionados
- Excision Repair of Uv Radiation-Induced DNA Damage in Caenorhabditis Elegans
- Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
- Radiation-induced chromosome damage in human lymphocytes
- Repair of Radiation-Induced Damage in Escherichia coli II. Effect of rec and uvr Mutations on Radiosensitivity, and Repair of X-Ray-Induced Single-Strand Breaks in Deoxyribonucleic Acid1
- Influence of anoxia on radiation-induced breaks in the Escherichia coli chromosome.