Renal failure in a patient with chronic lymphocytic leukaemia treated with fludarabine.

AUTOR(ES)

Macheta, M P

RESUMO

The case history of a man with refractory chronic lymphocytic leukaemia who developed acute renal failure following treatment with fludarabine is presented. A renal biopsy specimen showed features of mesangiocapillary glomerulonephritis, a rare occurrence in chronic lymphocytic leukaemia. The rapid cytocidal action of fludarabine may result in the development of renal glomerular lesions when used to treat a well differentiated B cell malignancy.

Documentos Relacionados

• Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia.
• Recurrent localised pneumonia due to bronchial infiltration in a patient with chronic lymphocytic leukaemia.
• Progressive multifocal leukoencephalopathy in a patient with relapsed chronic lymphocytic leukemia treated with Ibrutinib
• Acquired perforating dermatosis in a patient with chronic renal failure
• Autoimmunity in chronic lymphocytic leukaemia.