Relação entre a dosagem de etanol no sangue e na saliva

AUTOR(ES)

Marcos Vinicius Pinto Ventorin

DATA DE PUBLICAÇÃO

2004

RESUMO

The excessive use of alcoholic drink can cause a acute intoxication and a list of physical and mental disturbances know as acoholic intoxication, that involves subjects of juridical and forensic order. Usually the exam to detect the total level of alcohol in the patient is proceeded with the individual’s sample of blood collected, however another biological matrix can be used for analysis, as the urine, breath or saliva. There are several analytical methods for the quantification of the ethanol, being the chromatographic methods furthermore pratical and trustworthy apllication. The purpose of this study was to verify the use of the saliva as alternative matrix to the blood in research for the blood alcohol concentration through pratical method with reliable results, in cases of ingestion of alcoholic drinks. The evaluation was made in saliva samples collected in thirty volunteers that ingested 80ml of alcoholic drink under fast of three hours and period of abstinence of 48 hours for the use of drunk alcoholic and drugs in general. There were completion a questionnaire of health and signature of the consent term. The vaporized samples (headspace) of blood and saliva were analyzed by gas chromatographic. For the statistical analysis they were used Pearson’s correlation and the test-t pair with p<0.05. There was a loss of three samples, and the results refer to 27 samples. The ethanol average in the blood was 0.2641 with the standart deviation 0.12004 being respectively in the saliva 0.2322 and 0.11154. There was strong positive correlation showing similar behavior of the ethanol in the samples of blood and saliva (r=0.810 p<0.01), however the ethanol averages in the blood and saliva were different (t=0.029 p<0.05). The data of this study indicate that the saliva presented inferior values of ethanol than that blood indicates.

ASSUNTO(S)

cromatografia de gas bebidas alcoolicas

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