Regulation of the Fatty Acid Composition of the Membrane Phospholipids of Escherichia coli
AUTOR(ES)
Cronan, John E.
RESUMO
An increase in the dosage of the fabA gene, which codes for the enzyme β-hydroxydecanoyl thioesterase, causes an increase in the unsaturated fatty acyl content of the phospholipids. This increase is small in cells growing at a constant temperature. However, if cells grown at 37 or 42° are shifted to 15°, the rate of unsaturated fatty acyl moiety synthesis approaches twice the rate of a normal strain. These results indicate that the ratio of unsaturated to saturated fatty acyl groups in phospholipids is partially determined by the levels of at least this fatty acid biosynthetic enzyme.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=433856Documentos Relacionados
- CONTROL OF FATTY ACID COMPOSITION IN PHOSPHOLIPIDS OF Escherichia coli: RESPONSE TO FATTY ACID SUPPLEMENTS IN A FATTY ACID AUXOTROPH*
- Incorporation of Synthetic Fatty Acid Analogs into Phospholipids of Escherichia coli
- Turnover of Phospholipids in an Unsaturated Fatty Acid Auxotroph of Escherichia coli
- Regulation of fatty acid biosynthesis in Escherichia coli.
- Regulation of membrane fatty acid composition by temperature in mutants of Arabidopsis with alterations in membrane lipid composition
