Regulation of Polyglutamic Acid Synthesis by Glutamate in Bacillus licheniformis and Bacillus subtilis
AUTOR(ES)
Kambourova, Margarita
FONTE
American Society for Microbiology
RESUMO
The synthesis of polyglutamic acid (PGA) was repressed by exogenous glutamate in strains of Bacillus licheniformis but not in strains of Bacillus subtilis, indicating a clear difference in the regulation of synthesis of capsular slime in these two species. Although extracellular γ-glutamyltranspeptidase (GGT) activity was always present in PGA-producing cultures of B. licheniformis under various growth conditions, there was no correlation between the quantity of PGA and enzyme activity. Moreover, the synthesis of PGA in the absence of detectable GGT activity in B. subtilis S317 indicated that this enzyme was not involved in PGA biosynthesis in this bacterium. Glutamate repression of PGA biosynthesis may offer a simple means of preventing unwanted slime production in industrial fermentations using B. licheniformis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=92683Documentos Relacionados
- TRANSFORMATION TO PROTOTROPHY AND POLYGLUTAMIC ACID SYNTHESIS IN BACILLUS LICHENIFORMIS
- Regulated Enzymes of Aromatic Amino Acid Synthesis: Control, Isozymic Nature, and Aggregation in Bacillus subtilis and Bacillus licheniformis
- Peptidoglycan synthesis in L-phase variants of Bacillus licheniformis and Bacillus subtilis.
- Regulation of glutamate dehydrogenase in Bacillus subtilis.
- Positive regulation of glutamate biosynthesis in Bacillus subtilis.
