Regional differences in the distribution of dividing cells in hamster cheek pouch epithelium.
AUTOR(ES)
Scragg, M A
RESUMO
Examination of vinblastine-arrested metaphase figures in sections from the medial wall of 15 hamster cheek pouches showed that: (1) the distribution of dividing cells was non-random and (2) mitotic activity declined in an anteroposterior direction. Although there was some variation between different pouches these features were statistically significant (P less than 0.05) in individual pouches from half the animals and highly significant (P less than 0.005) when the data from all pouches were pooled. The average sample size required to determine a mitotic index representative of the whole length of the pouch was equivalent to approximately 32 mm of surface length of epithelium or 4562 basal cells. This estimate exceeds the sample size generally examined and it is suggested that inadequate sampling could account for some of the inconsistencies in the literature on hamster cheek pouch cell kinetic data.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1171953Documentos Relacionados
- Gender differences in microcirculation: Observation using the hamster cheek pouch
- Regional differences in the ultrastructural features of secretory cells in the golden hamster (Mesocricetus auratus) oviductal epithelium.
- Stereological studies of differentiation in hamster cheek pouch epithelium: variations in the volume and frequency of mitochondria.
- Distribution and ultrastructural characteristics of Feyrter cells in the rat and hamster airway epithelium.
- Volumetric alterations in tonofibrils during epithelial differentiation in hamster cheek pouch mucosa.
