Recurrent, Disseminated Mycobacterium marinum Infection Caused by the Same Genotypically Defined Strain in an Immunocompromised Patient

AUTOR(ES)

Holmes, G. Frank

FONTE

American Society for Microbiology

RESUMO

An 81-year-old male with myasthenia gravis developed a cutaneous infection with Mycobacterium marinum, which apparently resolved following local heat therapy. Five months later, the patient developed new skin lesions and pancytopenia. M. marinum was isolated from his bone marrow. Pulsed-field gel electrophoresis was performed to determine if the skin and bone marrow isolates were clonally related. Digestion of the genomic DNA with the restriction enzymes SpeI and AseI yielded indistinguishable banding patterns. An epidemiologically unrelated control strain showed significant banding differences. The results suggest that the patient’s recurrent, disseminated infection was due to recrudescence of his initial infection rather than reinfection by another strain.

Documentos Relacionados

• Bacteremia in an Immunocompromised Patient Caused by a Commensal Neisseria meningitidis Strain Harboring the Capsule Null Locus (cnl)
• Pseudotumour of the lung caused by Mycobacterium malmoense infection in an HIV positive patient
• Deep Infection by Trichophyton rubrum in an Immunocompromised Patient
• Recurrent epidermal cyst infection caused by Brucella melitensis in a diabetic patient.
• Mycobacterium thermoresistibile infection in an immunocompromised host.