Rectal diazepam in the treatment of absence status: a pharmacodynamic study

AUTOR(ES)

Milligan, Norman

RESUMO

Rectal administration of diazepam is highly effective in terminating absence status as judged by reduction of spike-wave activity in the EEG. Pharmacokinetic studies indicate that diazepam can have antiepileptic properties at serum levels well below those previously reported as being necessary to achieve a therapeutic effect.

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