Reconstruction of major maternal and paternal lineages of the Cape Muslim population
AUTOR(ES)
Isaacs, Shafieka, Geduld-Ullah, Tasneem, Benjeddou, Mongi
FONTE
Genet. Mol. Biol.
DATA DE PUBLICAÇÃO
19/04/2013
RESUMO
The earliest Cape Muslims were brought to the Cape (Cape Town -South Africa) from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they contributed to the ethnic diversity of the present Cape Muslim population of South Africa. The history of the Cape Muslims has been well documented and researched however no in-depth genetic studies have been undertaken. The aim of the present study was to determine the respective African, Asian and European contributions to the mtDNA (maternal) and Y-chromosomal (paternal) gene pool of the Cape Muslim population, by analyzing DNA samples of 100 unrelated Muslim males born in the Cape Metropolitan area. A panel of six mtDNA and eight Y-chromosome SNP markers were screened using polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP). Overall admixture estimates for the maternal line indicated Asian (0.4168) and African mtDNA (0.4005) as the main contributors. The admixture estimates for the paternal line, however, showed a predominance of the Asian contribution (0.7852). The findings are in accordance with historical data on the origins of the early Cape Muslims.
Documentos Relacionados
- Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population.
- Analysis of paternal lineages in Brazilian and African populations
- Equal Expression of the Maternal and Paternal Alleles for the Polypeptide Subunits of the Major Storage Protein of the Bean Phaseolus vulgaris L. 1
- Maternal and paternal age at delivery, birth order, and risk of childhood onset type 1 diabetes: population based cohort study
- Recombinant Rabbit Secretory Immunoglobulin Molecules: Alpha Chains with Maternal (Paternal) Variable-Region Allotypes and Paternal (Maternal) Constant-Region Allotypes