Quantitative Assessment of Hemadsorption by Myxoviruses: Anti-Immunoglobulin G Hemadsorption-Inhibition Test

AUTOR(ES)
RESUMO

A quantitative hemadsorption-inhibition test was developed to estimate myxovirus serum antibodies within 24 h by determining the serum dilution inhibiting hemadsorption in 50% of the infected cells. The test depends on the interactions of virus-infected cell monolayers with antiviral serum and of the resultant complexes with antiimmunoglobulin G serum. The incorporation of species-specific anti-immunoglobulin G serum into the test significantly increased sensitivity.

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