Pyrrolizidine alkaloids of senecio sp from Peru

AUTOR(ES)

Artiles, Liliana Ruiz Vásquez and Matías Reina, Coloma, Azucena González, Pérez, Raimundo Cabrera, Mesia, Lastenia Ruiz

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2011

RESUMO

Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species. The structures of these alkaloids were established by a complete NMR spectroscopic analysis, chemical transformations and comparison of their NMR data with those published for similar alkaloids. Three PAs were then tested for antifungal activity against Fusarium moniliforme, F. (Sheldon), F. oxysporum fs. lycopersici (Scheldt) and F. solani (Mart), no significant activity being observed.

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