Projeto, construção e testes de desempenho "In Vitro" de uma bomba de sangue centrifuga implantavel / Design, manufacture and performance tests "In Vitro" of an implantable centrifugal blood pump

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

An implantable centrifugal blood pump was developed for long-term ventricular assistance in cardiac patients. In vitro tests were performed, as wear evaluation, performance tests and hemolysis tests in human blood. Preliminary tests were performed with a non-implantable pump in order to properly locate the inlet port. Numerical computational simulations were performed in order to predict its best geometry. Wear evaluations helped to select the best materials for double pivot bearing system proposed to achieve longer durability. Performance tests pointed the best impeller geometry. The implantable centrifugal blood pump was compared with other two blood pumps. One is a centrifugal blood pump for cardiopulmonary bypass and the other is a similar implantable device. The proposed implantable centrifugal blood pump showed the best performance. But, its results showed a strong descendant curve in high flow. Other prototype was manufactured with a different inlet port angle to overcome this problem. The normalized index of hemolysis (NIH) tests was performed with human blood pumped in an In Vitro closed circuit (mock loop) in normalized conditions, as flow of 5 L/min and total pressure ahead of 100 mm Hg. After six hours, NIH measured 0.0054 mg/100L that can be considered excellent since it is close to the minimum found in literature (between 0.004 g/ 100L e 0.02 g/ 100L). As future work, in vivo test will be performed with the implantable centrifugal blood pump looking forward to implant it in patients

ASSUNTO(S)

hemolise e hemolisinas orgaos artificiais artificial heart biocompatibilidade ventricular assistance material ceramico sangue - circulação coração double pivot bearing system mancais

ACESSO AO ARTIGO

Documentos Relacionados